Instant hand sanitizer delivers advanced antimicrobial germ kill while being gentle to the skin. Scientifically advanced, patent-pending formulation kills more than 99.99 percent of most common germs. This alcohol-based hand sanitizer works in as little as 15 seconds with no water or towels needed. It provides unprecedented germ kill while soothing hands and maintaining skin health. Four different skin conditioning agents help maintain skin health, skin moisture and improved overall skin feel. 450 ml refill is designed for use with the PURELL ES Everywhere System.